1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. E1/E2/E3 Enzyme
  4. Casitas B-lineage lymphoma-b Isoform
  5. Casitas B-lineage lymphoma-b Inhibitor

Casitas B-lineage lymphoma-b Inhibitor

Casitas B-lineage lymphoma-b Inhibitor (1):

Cat. No. Product Name Effect Purity
  • HY-183293
    Cbl-b-IN-32
    Inhibitor
    Cbl-b-IN-32 is a Cbl-b inhibitor with an IC50 of 6.83 μM. Cbl-b-IN-32 binds to the TKB-LH interface, stabilizes the inactive conformation of Cbl-b, engages Tyr363 via hydrogen bonds and water bridges, and forms hydrogen bonds with Phe261 and Phe263.